• Opportunity to improve livestock traits using 3D genomics

    18 days ago - By Animal Genetics

    Summary
    The advent of high-throughput chromosome conformation capture and sequencing has enabled researchers to probe the 3D architecture of the mammalian genome in a genome-wide manner. Simultaneously, advances in epigenomic assays, such as chromatin immunoprecipitation and sequencing and DNase-seq, have enabled researchers to study cis-regulatory interactions and chromatin accessibility across the same genome-wide scale. The use of these data has revealed many unique insights into gene regulation and disease pathomechanisms in several model organisms. With the advent of these...
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