• The equine graying with age mutation of the STX17 gene: A copy number study using droplet digital PCR reveals a new pattern

    25 days ago - By Animal Genetics

    Summary
    The equine graying with age causative mutation in the syntaxin‐17 gene has been known for over a decade, but proper genotyping of this variant remains challenging due to its molecular character. Precise information on gray mutation status is important for horse breeders and veterinarians, since gray homozygous horses are more prone to developing aggressive melanoma tumors than heterozygotes. Since recent studies have confirmed that droplet digital PCR is a valuable technique for copy number analysis, we decided to investigate whether this method can be used for accurate genotyping...
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