• Assessment of the FAM174A 11G allele as a risk allele for equine metabolic syndrome

    5 monthes ago - By Animal Genetics

    Summary
    An 11G nucleotide repeat in the 3′ UTR of FAM174A was recently postulated as a risk allele with a dominant mode of inheritance for equine metabolic syndrome and laminitis status in Arabian horses. The objective of this project was to evaluate this hypothesis in a large and diverse across‐breed population. A total of 301 ponies, 292 Morgans, 64 Arabians, 49 Tennessee Walking Horses and 59 Quarter Horses were genotyped for six observed G repeat alleles in the FAM174A 3′ UTR. Phenotype data included laminitis status, baseline insulin, glucose, non‐esterified fatty acids...
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