• Food intake‐related genes in chicken determined through combinatorial genome‐wide association study and transcriptome analysis

    1 month ago - By Animal Genetics

    Summary
    The chicken gizzard is the primary digestive and absorptive organ regulating food intake and metabolism. Body weight is a typical complex trait regulated by an interactive polygene network which is under the control of an interacting network of polygenes. To simplify these genotype-phenotype associations, the gizzard is a suitable target organ to preliminarily explore the mechanism underlying the regulation of chicken growth through controlled food intake. This study aimed to identify key food intake‐related genes through combinatorial GWAS and transcriptome analysis. We performed...
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  • Genome‐wide association study of shank length and diameter at different developmental stages in chicken F2 resource population

    1 month ago - By Animal Genetics

    Abstract
    In order to find SNPs and genes affecting shank traits, we performed a GWAS in a chicken F2 population of eight half‐sib families from five hatches derived from reciprocal crosses between an Arian fast‐growing line and an Urmia indigenous slow‐growing chicken. A total of 308 birds were genotyped using a 60K chicken SNP chip. Shank traits including shank length and diameter were measured weekly from birth to 12 weeks of age. A generalized linear model and a compressed mixed linear model were applied to achieve the significant regions. The value of the average genomic inflation...
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