• A 51 bp indel polymorphism within the PTH1R gene is significantly associated with chicken growth and carcass traits

    5 monthes ago - By Animal Genetics

    Summary
    Parathyroid hormone is a crucial regulator of calcium homeostasis and bone remodeling, and the parathyroid hormone 1 receptor belongs to a class II G‐protein‐coupled receptor. PTH activates PTH1R, which mediates catabolic and anabolic processes in the skeleton. However, the functional mechanism of PTH1R has not been thoroughly elucidated in organisms. This study identified a 51 bp indel mutation in the first intron of the PTH1R gene and elucidated the effect of this gene mutation on the growth and carcass traits in chickens. The results indicated that the 51 bp indel was...
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