• Thoroughbred stallion fertility is significantly associated with FKBP6 genotype but not with inbreeding or the contribution of a leading sire

    13 days ago - By Animal Genetics

    Summary
    This is a follow-up study to validate the previously detected association of the FKBP6 gene with stallion subfertility. Using a select cohort of 150 Thoroughbred stallions with detailed breeding records, we confirm significant association between low per-cycle pregnancy rates and a combined A/A-A/A genotype of SNPs chr13:11 353 372G> A and chr13:11 353 436A> C in FKBP6 exon 5. We also show that stallion subfertility and the combined genotype A/A-A/A are not associated with the level of genetic diversity based on 12 autosomal microsatellite markers, or with pedigree-based inbreeding...
    Read more ...