• A mutation modulating DDX3Y gene expression cosegregates with the major Y‐chromosomal haplogroups and with testis size in Hu sheep

    18 days ago - By Animal Genetics

    Summary
    Variations in the Y-chromosome are usually correlated with male-specific traits. However, this condition has been described only sporadically, even in human genetics. The present study was conducted to clone the full-length gene sequence of ovine DEAD-box helicase 3, Y-linked , and investigate the effect of the expression and variation of DDX3Y on the reproductive traits of Hu sheep. Consequently, we identified the full coding sequence and genomic sequence of ovine DDX3Y. Quantitative PCR analysis showed that ovine DDX3Y was highly expressed in testis, and the expression level...
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